Get ready for an NFC West battle as the and the will face off at 4:25 p.m. ET on Sunday at State Farm Stadium. Arizona is 4-0 overall and 1 Mark Recchi Men Jersey -0 at home, while San Francisco is 2-2 overall and 2-0 on the road. The Cardinals easily handled the last Sunday, 37-20. San Francisco lost to the , 28-21. The Cardinals are the only undefeated team remaining in the NFL after four weeks. Arizona is favored by five points in the latest Cardinals vs. 49ers odds from Caesars Sportsbook, and the over-under is set at 48.5. Before entering any 49ers vs. Cardinals picks, . The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception Bryan Trottier Jersey six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 5 of the 2021 season on an incredible 124-82 run on top-rated that dates back to the 2017 season.The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.Now, the model has set its sights on . . Here are several for Justin Schultz Kids Jersey Niners vs. Cardinals:Cardinals vs. 49ers spread: Cardinals -5Cardinals vs. 49ers over-under: 48.5 points Featured Game | Arizona Cardinals vs. San Francisco 49ers Moneyline Spread Total ARI SF What you need to know about the Cardinals pa sed for two TDs and 268 yards on 32 attempts in addition to picking up 39 yards on the ground in the win over the Rams. He has 19 pa sing TDs and nine rushing TDs in his last nine home games. He is the only NFL QB with nine pa sing TDs and three rushing TDs this year. He has rushed for a score in two of his last three games vs. the 49ers. picked up 120 yards on the ground on 12 carries vs. Ron Francis Women Jersey the Rams and is tied for the NFC lead among RBs with 395 scrimmage yards. He will be a game-time decision this week because of a shoulder injury. had 22 catches for 199 yards in two games vs. San Francisco last year.What you need to know about the 49ers The 49ers lost to a calf injury last week after the first half. He was replaced by rookie , who pa sed for 157 yards and two TDs with no interceptions. He rushed for 41 yards and a two-point conversion. Lance will make his first NFL start this week against Arizona, as Garoppolo will be out.Lance threw a 76-yard TD pa s to in Week Antti Niemi Men Jersey 4. Samuel had eight catches for 156 yards and caught two TD pa ses for the first time in his career. He is one of two NFL wide receivers with two games of 150-plus yards so far this season. is doubtful for Week 5 because of a calf injury.How to make 49ers vs. Cardinals picksThe model is leaning over on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. .So who wins 49ers vs. Cardinals? And which side of the spread hits more than 50 percent of the time?.
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