Hypercholesterolemia Market Demand, Share, and Strategic Outlook

Hypercholesterolemia Market Projected to Expand at 3.2 % CAGR Through 2028

The Global Hypercholesterolemia Market is projected to grow at a CAGR of around 3.2% during the forecast period, i.e., 2023-28. The market is driven by the alarming rise in the prevalence of cardiovascular diseases and chronic disorders such as diabetes, obesity, and others worldwide. Elevated levels of non-HDL cholesterol and LDL in the blood may result in life-threatening conditions, including heart disease and stroke. According to WHO, raised total cholesterol is a major cause of disease burden in both the developed and developing world as a risk factor for ischemic heart disease and stroke. Globally, a third of ischaemic heart disease is due to high cholesterol. Overall, raised cholesterol is estimated to cause 2.6 million deaths (4.5% of total) and 29.7 million DALYS, or 2% of total DALYS.

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Strategic Takeaways from the Report:

Market Sizing and Forecasting
Regulatory and Policy Influence
Competitive Trends and M&A Activity
Innovation Drivers and Disruptive Technologies
Investment Hotspots and Emerging Niches
Geographical Dynamics and Trade Flows

Hypercholesterolemia Market Segment Overview & Classification

This market is categorized to offer targeted insights across various operational and consumer-related verticals.

Segment List:

By Disease Type

Genetic
Acquired

Between the two, the Genetic segment acquired the largest market share in the historical period with Familial Hypercholesterolemia (FH) as a common genetic disorder, remained prominent. According to the Centers for Disease Control and Prevention, more than one million people in the U.S. have familial hypercholesterolemia, but unfortunately, only about 30% know about it. Being an inherited disorder, FH makes it crucial to get family members tested in order to find more such cases.

By Treatment Type

Stains
Bile Acid Binding Resins
Niacin
PCSK9 Inhibitors
Cholesterol Absorption Inhibitors
Fibric Acid Derivatives
Others

By Distribution Channel

Retail Pharmacies
Hospitals Pharmacies
Online Pharmacies

By Region

North America
South America
Europe
The Middle East & Africa
Asia-Pacific.

On the geographical front, North America grabbed the maximum market share in 2022 and is anticipated to prevail in the same trend. The dominance of the region is primarily attributed to the growing awareness accompanied by the substantial healthcare expenditure by the respective governments. With more than one million people suffering from Familial Hypercholesterolemia in the US alone, the situation across the region continues to be life-threatening. Besides, recent instances of type-2 diabetes in adults and underrated thyroid levels, when paired with a lack of a wholesome diet, have brought the attention of researchers, & healthcare service providers and compelled them to come up with more effective solutions for the condition and, derived disorders in the past few years.

These divisions help clarify demand patterns and expected shifts.

Market Driver

Surging R&D Activities and Clinical Studies Drive Market Growth - Rising Research and development (R&D) activities associated with hypercholesterolemia and fueling clinical trials of the treatment drugs produced by major pharmaceutical manufacturers , drive market growth around the globe. Due to increasing changes in lifestyle and unhealthy diets, individuals have high bad cholesterol in their bloodstreams. The disease risk has increased with obesity, unhealthy lifestyle, intake of unhealthy food, and most importantly diabetes.

Moreover, according to the International Diabetes Federation (IDF), 1 in 10 individuals are suffering from hypercholesterolemia. Although 537 million adults are living with diabetes, 643 million adults are estimated to have diabetes by 2030. This reflects the high prevalence of hypercholesterolemia as diabetes increases the risk of hypercholesterolemia. Thus, anticipated to increase the CAGR value of Hypercholesterolemia Market around globe during the projected period.

In addition, North America accounted for a considerable share of Market in recent years due to increasing R&D activities and an increasing clinical studies number over the region. For instance,

In 2022, Ionic Pharmaceutical collaborated with AstraZeneca to release an antisense drug to lower blood cholesterol levels in hypercholesterolemia patients by targeting a protein, that is a proprotein convertase subtilisin/kexin type 9.

Hypercholesterolemia Market Competitive Snapshot from 2023-2028

The report highlights established and emerging players in the global Hypercholesterolemia Market, evaluating their strengths, challenges, and potential for innovation.

Key Competitors Include:

Novartis AG
Regeneron Pharmaceuticals
Merck KGaA
Pfizer
Astrazenca
AbbVie Inc.
Eli lily and Company
Espersion Therapeutics
Sanofi
Amgen Inc.
Teva Pharmaceutical
Aegerion Pharmaceuticals
Others.

Their activities include partnerships, product launches, and geographic expansions.

Hypercholesterolemia Industry Opportunity

Constant Advances in Genetic Therapies for FH To Bring Lucrative Prospects - The paradigm shifts in the treatment methods, paired with the rapid advancement in gene therapy technology in recent years, have revolutionized the way FH patients were treated earlier. Genetic therapies are being constantly developed for Familial Hypercholesterolemia and may bring absolute LDL-C dipping. Unlike existing lipid-lowering therapies, exhibiting difficulty in achieving lipid target levels in FH patients, Gene Therapy has shown excellent therapeutic potential. With further optimization of delivery efficiency, immunogenicity, and the precision of gene therapy, the market players may maximize their revenue in the coming years.

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